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OneNext 2025

Building Together the AI Continent

Developing the Next Generation Stack for Open and Decentralized Sovereign AI Factories at Scale

NOVEMBER 12-13, 2025

MIX BRUSSELS, BELGIUM

What is OneNext 2025?

OneNext 2025 will bring together leading industry stakeholders driving the development of sovereign AI Factories. The event will explore the key challenges in building the next generation of open, decentralized AI Factories and Gigafactories, leveraging HPC, cloud, and edge infrastructure as a strategic alternative to proprietary hyperscaler solutions. Building on the legacy of the OpenNebulaCon series, the 2025 edition will focus on how open cloud technologies are powering sovereign cloud environments and enabling next-generation AI Factories at scale.

The agenda will span all layers of the technology stack, bringing together the industrial ecosystem of the IPCEI-CIS initiative, the AI Factory efforts within EuroHPC, and key stakeholders from the cloud and telecom sectors. The program will feature thematic panels with C-level executives, directors, and leading experts who are shaping Europe’s AI and cloud infrastructure landscape, aimed at generating actionable recommendations for both industry and public-sector stakeholders. A final report will consolidate the collective outcomes of the event, ensuring anonymity and avoiding direct attribution of individual contributions.

Companies Behind Past OpenNebula Systems Events

Explore our previous events and discover highlights from our past conferences:

Let’s Build the AI Continent, Together!

Agenda Highlights

The event aims to address the critical need for a high-performance, distributed HPC-cloud-5G/edge continuum infrastructure that can support the growing demands of AI workloads and ultra-low-latency applications. We will discuss:

Scaling LLMs at Infrastructure Level

Challenges in the execution of large language models (LLMs) and AI frameworks at scale, including performance optimization, distributed deployment, data locality, and interoperability across heterogeneous infrastructure.

Cloud-Edge AI Architecture

Architectural directions required to build a scalable and diverse cloud-edge computing ecosystem, capable of supporting the full AI lifecycle—from training to inference—at scale.

5G & AI Continuum Connectivity

Connectivity requirements across this continuum, including the role of 5G and advanced networking, to ensure seamless workload distribution and real-time processing.

Sovereign AI Orchestration

Core components of a software platform needed for the orchestration and monitoring of AI workloads across heterogeneous HPC, cloud, and edge environments, with an emphasis on strategic sovereignty in all foundational layers.

OneNext 2025 Agenda 

Panel 1 - Industry Demand for Sovereign AI

Industry leaders discuss their real-world AI needs—performance, compliance, and operational integration—and how sovereign, open solutions can address these priorities.

Panel 2 - The Open Large Model Landscape

Focus on the development and deployment of open source large language models, covering challenges in data, compute, alignment, and collaborative innovation.

Panel 3 - AI Platforms and Workflows
Explores orchestration tools and software platforms that enable scalable AI workflows across hybrid environments, from training to inference.
Panel 4 - The Software Stack Behind Sovereign AI Factories
Examines the core software layers—virtualization, automation, storage, inference tools—that support secure and high-performance AI across hybrid and edge infrastructures.
Panel 5 - Infrastructure Components for AI Factories
Covers the role of next-gen hardware (CPUs, GPUs, accelerators) in shaping efficient, sovereign AI deployments, with emphasis on integration and open hardware initiatives.
Panel 6 - HPC for AI Factories
Discusses leveraging HPC to scale AI model training and fine-tuning, supporting hybrid architectures, and fulfilling performance/security needs for Sovereign AI.
Panel 7 - Cloud Providers and AI
Highlights how European cloud providers are adapting to support sovereign AI with accelerated hardware, data protection, and scalable infrastructure.
Panel 8 - Telcos and 5G / AI
Focuses on how telecoms are embedding AI into 5G networks, enabling edge intelligence, and reinforcing the telco role in sovereign, decentralized AI deployment.

Why Attend  OneNext 2025?

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Strategic Insights

Understand the opportunities and challenges in building open, decentralized AI Factories and large-scale infrastructures. Gain expert insights on how HPC, Telco, Cloud, and Edge technologies can create a next-gen AI stack—an alternative to proprietary, hyperscaler-dependent solutions.

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Valuable Networking

Connect with government representatives, AI innovators, and cloud experts to share knowledge, discover best practices, and build meaningful partnerships. Seize a unique opportunity to grow your business, develop innovative AI services, and stay ahead of evolving regulations.

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Actionable Knowledge

Leave with practical advice and strategic recommendations you can use right away. Topics include open virtualization, building decentralized AI Factories, and creating secure cloud environments for smarter decisions and long-term success.

Who should attend?

OneNext will bring together over a hundred decision-makers and industry professionals—including CIOs, CTOs, Heads of IT, IT Managers, Cloud Architects, Innovation Leads, AI Infrastructure Managers, Digital Policy Experts, and more—representing organizations such as:

  • Supercomputing centers evolving into AI Factories
  • Telecom providers developing sovereign edge services
  • Policymakers advancing digital sovereignty
  • Enterprises moving away from proprietary platforms
  • Cloud providers willing to deliver AI-as-a-Service
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    Our Venue

    Join us at Mix Brussels, a modern hotel with a spacious venue offering sleek facilities and a welcoming atmosphere—the ideal setting to connect with like-minded professionals and thought leaders while exploring big ideas.

    Apply Now to Attend

    This is a closed, invitation-only event. However, if you are actively involved in this space and believe you should participate, feel free to reach out to us for consideration.

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    This event is organized as part of the ONEnextgen project (UNICO IPCEI-2023-003), which is funded by the Spanish Ministry for Digital Transformation and Civil Service, and co-funded by the European Union’s NextGenerationEU through the RRF.